
Do you use a sharpening workflow which includes Capture Sharpen near the start of the process and Output Sharpen just before printing? If you aren't, you should be. But there are some workflow considerations. Quote from: Mark D Segal David is correct - we don't want to sharpen noise, so reduce the noise first and then sharpen. You can do it all in Lightroom where David correctly points out that the workflow order doesn't matter because the program looks after it under the hood it's just that these special purpose noise reduction plugins used with Photoshop - arguably - still do a better job at distinguishing noise from detail than does the current noise reduction feature in Lightroom. You could also design your own capture and output sharpeners from instructions provided in "Real World Image Sharpening." by Bruce Fraser and Jeff Schewe, but however you go about sharpening, reduce the noise first. These sharpeners are available from Photokit as a package and they are designed for this kind of workflow. You would send the image to Photoshop, use the noise reduction plugin on a duplicate image layer, then capture sharpen using for example a plugin such as Photokit Capture Sharpener Pro, finish adjusting and sizing your image for output, then do output sharpening using for example Photokit Output Sharpener. If you do that, you would not capture sharpen in Lightroom either, because you want to reduce the noise with the special purpose plugin first.


(See the various tutorials by Jeff Schewe and Jeff Schewe/Michael Reichmann on this subject.) Now, assuming you do, and depending on the seriousness of the noise, you may be better off reducing the noise outside of Lightroom using a special purpose plugin such as Noiseware or Noise Ninja, or Neat Image.

David is correct - we don't want to sharpen noise, so reduce the noise first and then sharpen.
